R&D theme 1
Development of early diagnosis and treatment methods for refractory cardiovascular disease to realize a resilient society

To perform basic / clinical research for the development of medicine and medical devices to improve quality of life and the prognoses for cardiomyopathy and severe ischemic heart disease, which are underlying diseases for heart failure, which has a poor prognosis.

R&D theme leader

NCVC Hospital (Director of Department of Heart Failure and Transplant)
IZUMI Chisato

Cooperating research institutes

Osaka University, Kansai Medical University, Towa Pharmaceutical Co., Ltd., Sysmex Corporation, Nipro Corporation, JSR Corporation, CYBERDYNE, Inc., crossEffect, Inc., Mediford Corporation

R&D theme 2
Achieving resilience through the development of new treatment methods for refractory cancer

While performing basic / clinical research to develop eradication methods for refractory cancers such as pancreatic cancer, basic / clinical research will be performed to develop optimal treatment methods, including palliative treatments, for advanced cancers that cannot be eradicated so that patients can live with the cancer without reducing their quality of life.

R&D theme leader

Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, Professor
SENO Hisorhi
*Visiting director of National Cerebral and Cardiovascular Center

Cooperating research institutes

Osaka University, Kobe University, Tokushima University, Wakayama Medical University, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Eisai Co., Ltd., Sysmex Corporation, JCR Pharma Co., Ltd., NEXGEN Co., Ltd.

R&D theme 3
Development of integrated life medicine to reduce the number of patients with dementia

In order to develop eradication methods for dementia, clinical data will be used in mathematical analyses and AI analyses on the onset and progression of dementia and basic research using animal models will also be performed. Community participation in the Kento bio-community will be encouraged, and clinical data from the elderly will be quantified and incorporated into onset prediction models. For advanced dementia that cannot be eradicated, basic / clinical research will be performed to develop optimal lifestyles so that patients can live with dementia without reducing their quality of life.

R&D theme leader

Kyoto University Graduate School of Medicine and Faculty of Medicine, Specially Appointed Professor
TAKAHASHI Ryosuke
*Visiting director of National Cerebral and Cardiovascular Center

Cooperating research institutes

Kobe University, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Shiga University of Medical Science, Kansai Medical University, Eisai Co., Ltd., Towa Pharmaceutical Co., Ltd., Sysmex Corporation

R&D theme 4
Comprehensive diagnosis and treatment strategies for fighting and overcoming emerging/re-emerging viral infections

To perform basic / clinical research to develop standard vaccines and compounds as a part of a bio-strategy for emerging/re-emerging viral infections in addition to optimizing a public health approach against viral infections that uses experience from COVID-19 (restricting people's movements and voluntary restraint).

R&D theme leader

Osaka University Center for Infections Disease Education and Research, Specially Appointed Professor
MATSUURA Yoshiharu
*Visiting director of National Cerebral and Cardiovascular Center

Cooperating research institutes

Tokushima University, Kobe University, Kyoto University, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Institute of Physical and Chemical Research (RIKEN), Eisai Co., Ltd., Sysmex Corporation

R&D theme 5
Sensory function impairments accompanying the four major diseases

The four major diseases may get worse when the sensory function impairments that accompany them deteriorate the patient's quality of life. While performing basic / clinical research to develop eradication methods for sensory function impairments, basic / clinical research will be performed for sensory function impairments that cannot be eradicated in order to develop optimal lifestyles so that patients can live with the sensory function impairments without reducing their quality of life.

R&D theme leader

Institute for Protein Research, Osaka University, Professor and deputy lab director
FURUKAWA Takahisa
*Visiting director of National Cerebral and Cardiovascular Center

Cooperating research institutes

Kobe University, Kyoto Prefectural University of Medicine, Kansai Medical University, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Nipro Corporation, CMIC HOLDINGS Co., Ltd.

R&D theme 6
Digital healthcare architecture

In addition to personal information (on checkups and treatments) collected by governments, businesses, and hospitals, scientific digital data on lifestyle (diet and exercise) and aging conditions will be used in healthcare as external environmental factors (the exposome).

R&D theme leader

Examination Section, Department of Lifestyle Diseases, National Cerebral and Cardiovascular Center, Specially appointed director
KOKUBO Yoshihiro

Cooperating research institutes

National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), JSR Corporation, CYBERDYNE, Inc., CMIC HOLDINGS Co., Ltd., Osaka Chamber of Commerce and Industry, Osaka Prefectural Government, Suita City, Settsu City

Consolidation issue 2
Promote and strengthen collaboration on each R&D issue (cultivate the next generation of researchers through hands-on education for young researchers)

R&D theme leader

Kyoto University Graduate School of Medicine and Faculty of Medicine, Specially Appointed Professor
MATSUDA Michiyuki

Participating institutions (universities, etc.)

National Institute of Biomedical Innovation, Health and Nutrition, The University of Tokushima, Kobe University, Kyoto University, Osaka University, Shiga University of Medical Science, Kobe Pharmaceutical University, Osaka Public University

Participating organizations (companies, etc.)

All participating institutions in the project

Consolidation issue 3
Implementation of the Health and Medical Data Platform Concept

R&D theme leader

Director, Information Management Department, National Cerebral and Cardiovascular Center
HIRAMATSU Haruhiko

Participating institutions (universities, etc.)

National Institute of Biomedical Innovation, Health and Nutrition, Suita, Settsu

Participating organizations (companies, etc.)

CMIC Holdings, Kowa, Japan Self-Care Promotion Council, Hankyu Hanshin Holdings, Wellier